COMPARATIVE SAFETY AND EFFECTIVENESS OF PERINATAL ANTIRETROVIRAL THERAPIES FOR HIV-INFECTED WOMEN AND THEIR CHILDREN: SYSTEMATIC REVIEW AND NETWORK META-ANALYSIS INCLUDING DIFFERENT STUDY DESIGNS.

Comparative safety and effectiveness of perinatal antiretroviral therapies for HIV-infected women and their children: Systematic review and network meta-analysis including different study designs.

BACKGROUND:Nearly all newly infected children acquire Human Immunodeficiency virus (HIV) via mother-to-child transmission (MTCT) during pregnancy, labour or breastfeeding from untreated HIV-positive mothers.Antiretroviral therapy (ART) is the standard care for pregnant women with HIV.However, evidence of ART effectiveness and harms in infants and c

read more

Haemophilus responses to nutritional immunity: epigenetic and morphological contribution to biofilm architecture, invasion, persistence and disease severity.

In an effort to suppress microbial outgrowth, the host sequesters essential nutrients in a process termed nutritional immunity.However, inflammatory responses to bacterial insult can restore nutritional resources.Given that nutrient availability modulates virulence factor production and biofilm formation by other bacterial species, we hypothesized

read more